研究テーマ(研究室紹介)

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疫学・予防分野では、環境要因(重金属、放射線)の健康影響、がんの疫学(喫煙との関係)に関して国内外で研究を行うとともに、母子保健、お茶の動脈硬化予防など鹿児島県における公衆衛生・地域保健と予防医学などの研究を行っています。

教育では、公衆衛生全般を担当するとともに、労働衛生の一部を担当しています。
主な社会貢献としては、郡山教授、上床助教が鹿児島県や市町村などの各種委員会に委員として参加して、公衆衛生施策に協力しています。

研究室概要

部局 医歯学総合研究科 Graduate School of Medical and Dental Sciences
専攻 健康科学 Health Research Course
大講座 人間環境学 Human and Environmental Sciences
分野 疫学・予防医学 Epidemiology and Preventive Medicine
分野サイト http://www.kufm.kagoshima-u.ac.jp/~p-health/(準備中)

分野サイト

連絡先

TEL.099-275-5298 / FAX.099-275-5299

主要研究テーマ

環境疫学(重金属、放射線、火山活動など) Environmental epidemiology on heavy metals, radiation and volcanic activity
癌の疫学 Cancer epidemiology
地域保健と労働衛生・予防医学 Community health, occupational health and preventive medicine
ウイルス関連がんの疫学 Epidemiology of virus related cancer

スタッフ


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教授
氏名 郡山千早 Chihaya KORIYAMA
専門分野 公衆衛生学、疫学
研究テーマ ・がんの疫学
・環境疫学

研究者総覧 リポジトリ


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助教
氏名 上床太心 Futoshi UWATOKO
専門分野 公衆衛生学、疫学
研究テーマ ・地域保健
・予防医学

研究者総覧 リポジトリ


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助教
氏名 ドゥルワ アティラ
DHRUVA Athira
専門分野 疫学
研究テーマ ・がんの疫学
・ウイルス関連癌

研究者総覧 リポジトリ

主な研究実績

  1. Ishidou Y, Koriyama C, Kakoi H, Setoguchi T, Nagano S, Hirotsu M, Yamamoto Y, Yokouchi M, Komiya S: Predictive factors of mortality and deterioration in performance of activities of daily living after hip fracture surgery in Kagoshima, Japan. Geriatrics and Gerontology International, 2017 Mar; 17(3):391-401.
  2. Tsuji M, Koriyama C, Yamamoto M, Anan A, Shibata E, Kawamoto T: The association between maternal psychological stress and inflammatory cytokines in allergic young children. PeerJ, 2016 Jan 18;4:e1585. Doi:10.7717/peerj.1585.eCollection 2016.
  3. Ordonez P, Nandakumar A, Koriyama C, Yamamoto M, Akiba S: Cytotoxic effect of NF-kB inhibitors in combination with anti-herpes agents on Epstein-Barr virus-positive gastric carcinoma in vitro. Molecular Medicine Reports, 2016 Jul 11. Doi: 10.3892/mmr.2016.5496. [Epub ahead of print],
  4. Yoshimoto K, Anh HT, Yamamoto A, Koriyama C, Ishibashi Y, Tabata M, Nakano A, Yamamoto M: Simple analysis of total mercury and methylmercury in seafood using heating vaporization atomic absorption spectrometry. Journal of Toxicological Sciences, 41: 489-500, 2016.
  5. Fujio S, Takano K, Arimura H, Habu M, Bohara M, Hirano H, Hanaya R, Nishio Y, Koriyama C, Kinoshita Y, Arita K: Treatable glomerular hyperfiltration in patients with active acromegaly. European Journal of Endocrinology, 2016 Jul 20. pii: EJE-16-0242. [Epub ahead of print].
  6. Tsukuya G, Samukawa T, Matsumoto K, Fukuyama S, Kumamoto T, Uchida A, Koriyama C, Ninomiya T, Inoue H: Comparison of the COPD Population Screener and International Primary Care Airway Group questionnaires in a general Japanese population: the Hisayama study. International Journal of Chronic Obstructive Pulmonary Disease, 2016, 11:1903-9.
  7. Lai HT, Koriyama C, Tokudome S, Tran HH, Tran LT, Nandakumar A, Akiba S, Le NT. Waterpipe tobacco smoking and gastric cancer risk among Vietnamese men. PLoS One. 2016 Nov 1;11(11):e0165587.
  8. Toyota M, Saigo Y, Higuchi K, Fujimura T, Koriyama C, Yoshiura T, Akiba S. Comparison of the peripheral doses from different IMRT techniques for pediatric head and neck radiation therapy. Radiat Prot Dosimetry. 2017 Feb 25:1-9. [Epub ahead of print]
  9. Samukawa T, Matsumoto K, Tsukuya G, Koriyama C, Fukuyama S, Uchida A, Mizuno K, Miyahara H, Kiyohara Y, Ninomiya T, Inoue H. Development of a self-scored persistent airflow obstruction screening questionnaire in a general Japanese population: the Hisayama study. International Journal of Chronic Obstructive Pulmonary Disease. 2017, 12:1469-81.
  10. Nandakumar A, Uwatoko F, Yamamoto M, Tomita K, Majima H, Akiba S, Koriyama C. Radiation-induced Epstein-Barr virus reactivation in gastric cancer cells with latent EBV infection. Tumor Biology, 2017 Jul; 39(7):1010428317717718. doi: 10.1177/ 1010428317717718. PubMed PMID: 28675108.
  11. Jinguji M, Nakajo M, Koriyama C, Yoshiura T. Thymic Involution after Radioiodine Therapy for Graves' Disease: Relationships with Serum Thyroid Hormones and TRAb. Journal of the Endocrine Society. 2017 Jun 5;1(7): 852-560.
  12. Ko KP, Yeo Y, Yoon JH, Kim CS, Tokudome S, Ngoan LT, Koriyama C, Lim YK, Chang SH, Shin HR, Kang D, Park SK, Kang CH, Yoo KY. Plasma phytoestrogens concentration and risk of colorectal cancer in two different Asian populations. Clinical Nutrition. 2017 Jul 18. pii: S0261-5614(17)30255-8. doi: 10.1016/j.clnu.2017.07.014. [Epub ahead of print] PubMed PMID: 28778370.
  13. Hoang VAT, Do HTT, Agusa T, Koriyama C, Akiba S, Ishibashi Y, Sakamoto M, Yamamoto M. Hair mercury levels in relation to fish consumption among Vietnamese in Hanoi. The Journal of Toxicological Sciences. 2017, 42(5): 651-62.
  14. Matsunaga S, Miyaguchi F, Kawabata N, Kuroshima T, Koriyama C. Cost-effectiveness of therapeutic drugs for the prevention of incident vertebral fracture in patients with postmenopausal osteoporosis -Randomized controlled trial of 72 week follow-up. Journal of Clinical & Experimental Orthopaedics. 2017, 3(3):39.
  15. Tran LT, Lai HTM, Koriyama C, Uwatoko F, Akiba S. The association between high birth weight and the risks of childhood CNS tumors and leukemia: an analysis of a US case-control study in an epidemiological database. BMC Cancer. 2017, 17(1):687. Doi:10.1186/s12885-017-3681-y.
  16. Aryal B, Shimizu T, Kadono J, Furoi A, Komokata T, Kitazono I, Koriyama C, Yamakuchi M, Hashiguchi T, Imoto Y. Post-resection exhaustion of intra-platelet serotonin: Also an indicator of early hepatocellular carcinoma recurrence? J Cancer, 2017 Oct 23; 8(19): 3984-3991, doi: 10.7150/jca.20971. eCollection 2017.
  17. Yasuhiro Ishihara, Nami Ikeda-Ishihara, Chihaya Koriyama, Noriaki Kakiuchi, Masayuki Tanaka, Christoph F.A. Vogel, Toshihiro Kawamoto, Tsuji Mayumi. Determination of chemical-specific IgGs in serum by an enzyme-linked immunosorbent assay with partial peptides of human serum albumin. J Toxicol Sci. 2018, 43(1):25-31.
  18. Mineshi Sakamoto, Laurie Chan, Jose Domingo, Chihaya Koriyama, Katsuyuki Murata. Kinetics of methylmercury, selenium, vitamin E, and docosahexaenoic acid: maternal and fetal transfer. Environment International, 2017 Nov 14. pii: S0160-4120(17)31561-1. doi: 10.1016/j.envint.2017.11.001.
  19. Juliet David, Athira Nandakumar, Muflihatul Muniroh, Suminori Akiba, Megumi Yamamoto, Chihaya Koriyama. Suppression of methylmercury-induced MIP-2 expression by N-acetyl-L-cysteine in murine RAW264.7 macrophage cell line. European Journal of Medical Research, 2017 Nov 9;22(1):45. doi: 10.1186/s40001-017-0287-4
  20. Shintaro Yanazume, Yuji Orita, Chihaya Koriyama, Yuichiro Niihara, Masaki Kamino, Shinichi Togami, Tsutomu Douchi, Hiroaki Kobayashi. Impact of subcutaneous drainage on wound disruption in gynecological malignancy surgery. Kagoshima Journal of Obstetrics and Gynecology, 2017 25: 14-21.
  21. Tomoko Ueyama, Takeshi Arimura, Koji Takumi, Fumihiko Nakamura, Ryutaro Higashi, Soichiro Ito, Yoshihiko Fukukura, Tomokazu Umanodan, Masanori Nakajo, Chihaya Koriyama, Takashi Yoshiura. Risk factors for radiation pneumonitis after stereotactic radiation therapy for lung tumours: clinical usefulness of the planning target volume to total lung volume ratio. British Journal of Radiology, 2018 Apr 16: 20170453. doi: 10.1259/bjr.20170453. [Epub ahead of print]
  22. Mayumi Tsuji, Yasuhiro Ishihara, Toyohi Isse, Chihaya Koriyama, Megumi Yamamoto, Noriaki Kakiuchi, Hsu-Sheng Yu, Masayuki Tanaka, Takuto Tsuchiya, Masanori Ohta, Rie Tanaka, Toshihiro Kawamoto. Evaluation of chemical-specific IgG antibodies in male workers from a urethane foam factory. Environmental Health and Preventive Medicine, 2018 23:24.
  23. Shinmura K, Choi YH, Shimohira M, Baba Y, Ikeda S, Hayashi S, Shibamoto Y, Koriyama C, Yoshiura T. Comparison of conservative treatment versus transcatheter arterial embolisation for the treatment of spontaneously ruptured hepatocellular carcinoma. Pol J Radiol. 2018 Jun 22;83:e311-e318. doi: 10.5114/pjr.2018.77024. eCollection 2018.
  24. Mayumi Tsuji, Eiji Shibata; Seiichi Morokuma; Rie Tanaka; Ayako Senju; Shunsuke Araki; Masafumi Sanefuji; Chihaya Koriyama; Megumi Yamamoto; Yasuhiro Ishihara; Koichi Kusuhara; Toshihiro Kawamoto; Japan Environment & Children's Study Group JECS. The association between whole blood concentrations of heavy metals in pregnant women and premature births: The Japan Environment and Children's Study (JECS). Environmental Research 2018 Oct;166:562-569. doi: 10.1016/j.envres.2018.06.025. Epub 2018 Jun 28
  25. Mayumi Tsuji, Chihaya Koriyama, Yasuhiro Ishihara, Christoph F.A. Vogel, Toshihiro Kawamoto. Association between bisphenol A diglycidyl ether-specific IgG in serum and food sensitization in young children. European Journal of Medical Research, 2018 Dec 26;23(1):61. doi: 10.1186/s40001-018-0358-1
  26. Mayumi Tsuji, Chihaya Koriyama, Yasuhiro Ishihara, Megumi Yamamoto, Kiwako Yamamoto-Hanada, Kumiko Kanatani, Yu Ait Bamai, Kazunari Onishi, Ayako Senju, Shunsuke Araki, Eiji Shibata, Seiichi Morokuma, Masafumi Sanefuji, Hiroshi Kitazawa, Mayako Saito, Masakazu Umezawa, Atsuto Onoda, Koichi Kusuhara, Rie Tanaka, Toshihiro Kawamoto, and the Japan Environment & Children’s Study Group. Associations between metal levels in whole blood and IgE concentrations in pregnant women based on data from the Japan Environment and Children’s Study. Journal of Epidemiology 2019 Jan 12. doi: 10.2188/jea.JE20180098. [Epub ahead of print]
  27. Ananthakrishnakurup Sreekumar, PadmavathyAmma Jayalekshmi, Athira Nandakumar, Raghu Ram K. Nair, Riyaz Ahammed, Paul Sebastian, Chihaya Koriyama, Suminori Akiba, Seiichi Nakamura, Junji Konishi. Thyroid Nodule Prevalence among Women in Areas of High Natural Background Radiation, Karunagappally, Kerala, India. Endocrine 2019 Oct 21. doi: 10.1007/s12020-019-02071-z. [Epub ahead of print]
  28. Kawaike Y, Nagata J, Furuya T, Koriyama C, Nakamura M, Sano A. Working memory-related prefrontal hemodynamic responses in university students: A correlation study of subjective well-being and lifestyle habits. Frontiers in Behavioral Neuroscience 2019, Sep 13;13:213. doi: 0.3389/fnbeh.2019.00213. eCollection 2019.
  29. Aryal B, Yamakuchi M, Shimizu T, Kadono J, Furoi A, Gejima K, Komokata T, Koriyama C, Hashiguchi T, Imoto Y. Predictive value of diminished serum PDGF-BB after curative research of hepatocellular cancer. J Oncology 2019 Jan 6;2019:1925315. Doi: 10.1155/2019/1925315. eCollection 2019.
  30. Juliet David, Muflihatul Muniroh, Athira Nandakumar, Mayumi Tsuji, Chihaya Koriyama, Megumi Yamamoto. Hg2+- induced MIP-2 expression was suppressed by N-acetyl-L-cysteine in RAW264.7 macrophages. Biomedical Reports 2020 Feb;12(2):39-45. doi: 10.3892/br.2019.1263. Epub 2019 Dec 3
  31. Muflihatul Muniroh, Ainun Rahmasari Gumay, Darmawati Ayu Indraswari, Yuriz Bahtiar, Hardian Hardian, Saekhol Bakri, Nani Maharani, Vega Karlowee, Chihaya Koriyama, Megumi Yamamoto. Activation of MIP-2 and MCP-5 expression in methylmercury-exposed mice and their suppression by N-acetyl-L-cysteine. Neurotoxicity Research (2020). https://doi.org/10.1007/s12640-020-00174-4

産学連携

郡山千早、上床太心
  1. 緑茶飲用介入による生活習慣病関連バイオマーカーの変化に関する研究 (志布志市)
  2. 緑茶飲用介入による生活習慣病関連バイオマーカーの変化に関する研究 (南九州市)
  3. ボタンボウフウ摂取による健康影響に関する介入研究(南さつま市)
  4. 脳卒中対策モデル地区事業「幸血圧プロジェクト」(南さつま市)
  5. 国保ヘルスアップ事業(医療費分析)(鹿児島県)

主な研究費取得状況

郡山千早
事業・種目 / 期間研究
科学研究費(基盤研究(B))
平成28年度~平成30年度(分担)
鯨・マグロ類多食集団における高濃度メチル水銀曝露の健康影響の解明及び介入研究
厚生労働科学研究費(成育疾患克服等次世代育成基盤研究事業(健やか世代育成総合研究事業))
平成29年度~令和元年度(分担)
HTLV-1母子感染予防に関するエビデンス創出のための研究
革新的技術課発・緊急展開事業(うち地域戦略プロジェクト)
平成29年度~令和元年度(分担)
血合肉すり身化技術による海外向け和食ヘルスケア食品の開発
科学研究費 基盤研究(C)
平成25年度~平成27年度 
喫煙と乳がんリスクにおける宿主要因との相互作用:閉経の有無別による検討
労災疾病臨床研究事業
平成26年度~平成28年度(分担)
化学物質特異的IgGのアレルギー診断と曝露モニタリングへの有用性に関する調査
日本医療研究開発機構
平成27年度~平成29年度(分担)
個人の生活習慣等の環境要因と遺伝的リスクを考慮した科学的根拠に基づく効率的な乳がん予防法の開発研究
上床太心 
事業・種目 / 期間研究
科学研究費(挑戦萌芽)
平成29年度~令和2年度(予定)
他職種協働による認知機能・自動車運転技能評価と包括的支援の効果の検証
科学研究費 基盤研究(挑戦萌芽)
平成26年度~平成28年度
母子保健および少子化対策は、いかなるソーシャルキャピタルを活用すべきか

分野サイト

新ニーズに対応する九州がんプロ養成プラン
GPなど(医歯学)
鹿児島大学
鹿児島大学病院
附属施設等
公開講座のご案内