• Research outline
• Research interests
• Staff
• Research results
• Research Grant List

Research outline

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Research interests

• Molecular genetical study of neuropsychiatryic disorders
• Molecular biological study of neuropsychiatryic disorders
• Clinical study of neuropsychiatryic disorders
• Surveillance study of chorea-acanthocytosis

Staff

Associate Professor

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Lecturer

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Assistant Professor

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特任研究員

Researche Repository

特任研究員

Researche Repository

Research results

Masayuki NAKAMURA

1. The human serotonin transporter gene linked polymorphism (5-HTTLPR) shows ten novel allelic variants, Mol Psychiatry 5: 32-38, 2000
2. The silencer activity of the novel human serotonin transporter linked polymorphic regions, Neurosci Lett 327: 13-16, 2002
3. N-terminal proteolysis of full-length mutant huntingtin in an inducible PC12 cell model of Huntington's disease. Cell Cycle 6: 2970-2981, 2007
4. Expansions of intronic TTTCA and TTTTA repeats in benign adult familial myoclonic epilepsy. Nat. Genet. 50: 581-590, 2018
5. Novel pathogenic VPS13A gene mutations in Japanese patients with chorea-acanthocytosis. Neurol. Genet., 5: e332, 2019

Hiroshi KIMOTSUKI

1. Dexmedetomidine aggravates cerebral ischemia in rats. Circulation Control 25: 50-55,2004．
2. Migration of neutrophils elicited by leukotriene B₄ is inhibited by fasudil, a Rho-kinase inhibitor, in the microvasculature of hamster cheek pouch. Circulation Control 25: 267-271, 2004.
3. 脳器質性変化を伴う高齢者のうつ病の診断と治療に関する実態調査―アルツハイマー病と脳血管障害. 老年精神医学雑誌 20: 445-452, 2009.
4. 難治性気分障害の治療―エビデンスレビューアルツハイマー病または脳血管障害を伴ううつ病の治療ガイドライン. 臨床精神医学 38: 1083-1092, 2009.

Nari SHIOKAWA

1. Chorein, the protein responsible for chorea-acanthocytosis, interacts with β-adducin and β-actin. Biochem Biophys Res Commun 441: 96-101, 2013

Takanori ISHIZUKA

1. Familial semantic dementia with P301L mutation in the Tau gene. Dement Geriatr Cogn Disord 31: 334-40, 2011
2. Different clinical phenotypes in siblings with a presenilin-1 P264L mutation. Dement Geriatr Cogn Disord 33: 132-40, 2012
3. 認知症症状を呈した高齢初発てんかん4例. 精神科 25: 555-560, 2014.

Natsuki SASAKI

1. Chorein interacts with α-tubulin and histone deacetylase 6, and overexpression preserves cell viability during nutrient deprivation in human embryonic kidney 293 cells. FASEB J. 30: 3726-3732, 2016

Hitoshi SAKIMOTO

1. 認知症症状を呈した高齢初発てんかん4例. 精神科 25: 555-560, 2014.
2. A new phenotype of mitochondrial disease characterized by familial late-onset predominant axial myopathy and encephalopathy. Biochem Biophys Res Commun 472: 118-24, 2016

Hanae HIWATASHI

1. 2-Methyl-5-pyridyl 2-(Substituted-phenoxy)-ethyl Esters with Precocious Metamorphosis-Inducing Activity. J Psticide Sci 26: 390-2, 2001

Izumi YOKOYAMA

1. Sakimoto H, Nakamura M, Nagata O, Yokoyama I, Sano A. Phenotypic abnormalities in a chorea-acanthocytosis mouse model are modulated by strain background. Biochem Biophys Res Commun. 2016 Mar 25;472(1):118-24.
2. Tomomi Kiyota, PhD; Yaman Lu, BSN; Bhagyalazmi Dyavashetty, BS, MS; Maryam Nemati, MD; Izumi Yokoyama, BS; R. Lee Mosley, PhD; Howard E. Gendelman, MD Granulocyte-macrophage colony-stimulating factor neuroprotective activities in Alzheimer’s disease mice Journal of Neuroimmunology. 15 June 2018

Patents and copy Rights

Research Grant List

Masayuki NAKAMURA

Takanori ISHIZUKA

Natsuki SASAKI

Hitishi SAKIMOTO

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