• Research outline
• Research interests
• Staff
• Research results
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Research outline

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Research interests

Feeding and body weight regulation, Eating disorders, Translational research in cashexia, Integrative medicine for cancer, Life style related diseases, Behavioral and psychological research on psychosomatic diseases, Functional gastrointestinal disorders, Japanese Kampo medicine

Staff

Professor

Researche Repository

Senior Assistant Professor

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Senior Assistant Professor

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Assistant Professor

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Visiting Assistant Professor 

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Project Researcher

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Project Researcher

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Research results

Akihiro Asakawa

1. 1. Asakawa A, Inui A, Ueno N, Makino S, Fujino MA, Kasuga M: Urocortin reduces food intake and gastric emptying in lean and ob/ob obese mice. Gastroenterology 116:1287-1292,1999

   2. Asakawa A, Inui A, Kaga T, Yuzuriha H, Nagata T, Ueno N, Makino S, Fujimiya M, Niijima A, Fujino MA, Kasuga M: Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin. Gastroenterology 120:337-345,2001

   3. Asakawa A, Inui A, Yuzuriha H, Ueno N, Katsuura G, Fujimiya M, Fujino MA, Niijima A, Meguid MM, Kasuga M: Characterization of the effects of pancreatic polypeptide in the regulation of energy balance. Gastroenterology 124:1325-1336,2003

   4. Asakawa A, Inui A, Kaga T, Katsuura G, Fujimiya M, Fujino MA, Kasuga M: Antagonism of ghrelin receptor reduces food intake and body weight gain in mice. Gut 52:947-952,2003

   5. Chen CY, Inui A, Asakawa A, Fujino K, Kato I, Chen CC, Ueno N, Fujimiya M: Des-acyl ghrelin acts by CRF type 2 receptors to disrupt fasted stomach motility in conscious rats. Gastroenterology 129:8-25,2005

   6. Inoue H, Ogawa W, Asakawa A, Okamoto Y, Nishizawa A, Matsumoto M, Teshigawara K, Matsuki Y, Watanabe E, Hiramatsu R, Notohara K, Katayose K, Okamura H, Kahn CR, Noda T, Takeda K, Akira S, Inui A, Kasuga M: Role of hepatic STAT3 in brain-insulin action on hepatic glucose production. Cell Metab 3:267-275,2006

   7. Fujitsuka N, Asakawa A, Hayashi M, Sameshima M, Amitani H, Kojima S, Fujimiya M, Inui A: Selective serotonin reuptake inhibitors modify physiological gastrointestinal motor activities via 5-HT2c receptor and acyl ghrelin. Biol Psychiatry 65:748-759,2009

   8. Urabe H, Kojima H, Chan L, Terashima T, Ogawa N, Katagi M, Fujino K, Kumagai A, Kawai H, Asakawa A, Inui A, Yasuda H, Eguchi Y, Oka K, Maegawa H, Kashiwagi A, Kimura H: Haematopoietic cells produce BDNF and regulate appetite upon migration to the hypothalamus. Nat Commun 4:1526,2013

   9. Takagi K, Legrand R, Asakawa A, Amitani H, François M, Tennoune N, Coëffier M, Claeyssens S, do Rego JC, Déchelotte P, Inui A, Fetissov SO: Anti-ghrelin immunoglobulins modulate ghrelin stability and its orexigenic effect in obese mice and humans. Nat Commun 4:2685,2013

   10. Fujitsuka N, Asakawa A, Morinaga A, Amitani M, Amitani H, Katsuura G, Sawada Y, Sudo Y, Uezono Y, Mochiki E, Sakata I, Sakai T, Hanazaki K, Yada T, Yakabi K, Sakuma E, Ueki T, Niijima A, Nakagawa K, Okubo N, Takeda H, Asaka M, Inui A: Increased ghrelin signaling prolongs survival in mouse models of human aging through activation of sirtuin. Mol Psychiatry 21:1613-1623,2016

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