FIELD

Research outline

photo all re

Graduate School Graduate School of Medical and Dental Sciences
Course Health Research Cource
Field Social and Behavioral Medicine
Department Psychosomatic Internal Medicine
Homepage http://www.kufm.kagoshima-u.ac.jp/~psm/

Homepage

Contact

TEL.+81-99-275-5751 / FAX.+81-99-275-5749

Research interests

Feeding and body weight regulation, Eating disorders, Translational research in cashexia, Integrative medicine for cancer, Life style related diseases, Behavioral and psychological research on psychosomatic diseases, Functional gastrointestinal disorders, Japanese Kampo medicine

Staff

 

Professor
Name Akihiro ASAKAWA
Specialized field Psychosomatic Internal Medicine
Research interests Intractable disease, complete cure, disease prevention, health promotion, anti-aging, terminal care

Researche Repository


 

Senior Assistant Professor
Name Robert Alan SLOAN
Specialized field Public health
Research interests Disease prevention, health promotion

Researche Repository


 

Assistant Professor
Name Yuuki FUKU
Specialized field Psychosomatic Internal Medicine
Research interests Intractable disease, complete cure, disease prevention, health promotion, anti-aging, terminal care

Researche Repository


 

Visiting Assistant Professor 
Name Takuro SONODA
Specialized field Japanese Kampo medicine
Research interests Japanese Kampo medicine

Researche Repository


 

Project Researcher
Name Goro KATSUURA
Specialized field Endocrinology and metabology
Research interests Basic research into the mechanism of appetite and feeding, basic research of complementary medicine

Researche Repository


 

Project Researcher
Name Namiko Kawamura
Specialized field Endocrinology and metabology
Research interests Basic research into the mechanism of appetite and feeding

Researche Repository

Research results

Akihiro Asakawa
    1. Asakawa A, Inui A, Ueno N, Makino S, Fujino MA, Kasuga M: Urocortin reduces food intake and gastric emptying in lean and ob/ob obese mice. Gastroenterology 116:1287-1292,1999

    2. Asakawa A, Inui A, Kaga T, Yuzuriha H, Nagata T, Ueno N, Makino S, Fujimiya M, Niijima A, Fujino MA, Kasuga M: Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin. Gastroenterology 120:337-345,2001

    3. Asakawa A, Inui A, Yuzuriha H, Ueno N, Katsuura G, Fujimiya M, Fujino MA, Niijima A, Meguid MM, Kasuga M: Characterization of the effects of pancreatic polypeptide in the regulation of energy balance. Gastroenterology 124:1325-1336,2003

    4. Asakawa A, Inui A, Kaga T, Katsuura G, Fujimiya M, Fujino MA, Kasuga M: Antagonism of ghrelin receptor reduces food intake and body weight gain in mice. Gut 52:947-952,2003

    5. Chen CY, Inui A, Asakawa A, Fujino K, Kato I, Chen CC, Ueno N, Fujimiya M: Des-acyl ghrelin acts by CRF type 2 receptors to disrupt fasted stomach motility in conscious rats. Gastroenterology 129:8-25,2005

    6. Inoue H, Ogawa W, Asakawa A, Okamoto Y, Nishizawa A, Matsumoto M, Teshigawara K, Matsuki Y, Watanabe E, Hiramatsu R, Notohara K, Katayose K, Okamura H, Kahn CR, Noda T, Takeda K, Akira S, Inui A, Kasuga M: Role of hepatic STAT3 in brain-insulin action on hepatic glucose production. Cell Metab 3:267-275,2006

    7. Fujitsuka N, Asakawa A, Hayashi M, Sameshima M, Amitani H, Kojima S, Fujimiya M, Inui A: Selective serotonin reuptake inhibitors modify physiological gastrointestinal motor activities via 5-HT2c receptor and acyl ghrelin. Biol Psychiatry 65:748-759,2009

    8. Urabe H, Kojima H, Chan L, Terashima T, Ogawa N, Katagi M, Fujino K, Kumagai A, Kawai H, Asakawa A, Inui A, Yasuda H, Eguchi Y, Oka K, Maegawa H, Kashiwagi A, Kimura H: Haematopoietic cells produce BDNF and regulate appetite upon migration to the hypothalamus. Nat Commun 4:1526,2013

    9. Takagi K, Legrand R, Asakawa A, Amitani H, François M, Tennoune N, Coëffier M, Claeyssens S, do Rego JC, Déchelotte P, Inui A, Fetissov SO: Anti-ghrelin immunoglobulins modulate ghrelin stability and its orexigenic effect in obese mice and humans. Nat Commun 4:2685,2013

    10. Fujitsuka N, Asakawa A, Morinaga A, Amitani M, Amitani H, Katsuura G, Sawada Y, Sudo Y, Uezono Y, Mochiki E, Sakata I, Sakai T, Hanazaki K, Yada T, Yakabi K, Sakuma E, Ueki T, Niijima A, Nakagawa K, Okubo N, Takeda H, Asaka M, Inui A: Increased ghrelin signaling prolongs survival in mouse models of human aging through activation of sirtuin. Mol Psychiatry 21:1613-1623,2016

Patents and copy Rights

titleinventorNo.
Remedies for Hyponutrition Status Akio INUI、Akihiro ASAKAWA、Toshihiro KAGA WO 02/060472 A1
Remedies for Diabetes Akio INUI, Akihiro ASAKAWA WO 2004/004772 A1
Novel Uses of Prostaglandin D2, Prostaglandin D2 Agonist and Prostaglandin D2 Antagonist Masaaki YOSHIKAWA, Kuniko TAKAGI, Kousaku OHINATA, Akio INUI, Akihiro ASAKAWA

WO 2004/030674 A1

Anti-cachexia agents Akio INUI, Akihiro ASAKAWA Japanese Patent No. P5692785
Anti-Ghrelin Antibodies and Uses thereof Akio INUI, Akihiro ASAKAWA WO 2014/170362 A1

 

 

Homepage