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• Research interests
• Staff
• Research results

Research outline

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Research interests

Staff

教授（兼任）

Researche

特任講師

Researche

特任講師

Researche

Research results

Mitsuru OHISHI

1. Kubozono T, Akasaki Y, Kawasoe S, Ojima S, Kawabata T, Makizako H, Kuwahata S, Takenaka T, Maeda M, Ohno M, Kijimuta M, Fujiwara S, Miyagawa K, Ohishi M.
   The relationship between home blood pressure measurement and room temperature in a Japanese general population.
   Hypertens Res 2021; 44: 454-463.
2. Kuwahata S, Takenaka T, Motoya T, Masuda K, Yonezawa H, Shinchi S, Kawashima Y, Mohri S, Ohishi M.
   Effect of QT prolongation in patients taking cholinesterase inhibitors (Donepezil) for alzheimer's disease.
   Circ Rep 2021; 3: 115-121.
3. Ninomiya Y, Kawasoe S, Kubozono T, Tokushige A, Ichiki H, Miyahara H, Tokushige K, Ohishi M.
   Sex-specific relationship between abdominal obesity and new-onset atrial fibrillation in the general Japanese population.
   Heart Vessels 2021; 36: 1879-1884.
4. Ninomiya Y, Inoue K, Tanaka N, Okada M, Tanaka K, Onishi T, Hirao Y, Oka T, Inoue H, Takayasu K, Nakamaru R, Kitagaki R, Koyama Y, Okamura A, Iwakura K, Ohishi M, Fujii K.
   Absence of first-pass isolation is associated with poor pulmonary vein isolation durability and atrial fibrillation ablation outcomes.
   J Arrhythm 2021; 37: 1468-1476.
5. Kawasoe S, Kubozono T, Ojima S, Kawabata T, Miyahara H, Tokushige K, Ohishi M.
   J-shaped curve for the association between serum uric acid levels and the prevalence of blood pressure abnormalities.
   Hypertens Res 2021; 44: 1186-1193.
6. Arikawa R, Kanda D, Ikeda Y, Tokushige A, Sonoda T, Anzaki K, Ohishi M.
   Prognostic impact of malnutrition on cardiovascular events in coronary artery disease patients with myocardial damage.
   BMC Cardiovasc Disord 2021; 21: 479.
7. Ojima S, Kubozono T, Kawasoe S, Kawabata T, Miyahara H, Tokushige K, Ohishi M.
   Gender differences in the risk factors associated with atherosclerosis by carotid intima-media thickness, plaque score, and pulse wave velocity.
   Heart Vessels 2021; 36: 934-944.
8. Sasaki Y, Ikeda Y, Uchikado Y, Akasaki Y, Sadoshima J, Ohishi M.
   Estrogen plays a crucial role in Rab9-dependent mitochondrial autophagy, delaying arterial senescence.
   J Am Heart Assoc 2021; 10: e019310.
9. Iwatani N, Kubota K, Ikeda Y, Tokushige A, Miyanaga S, Higo K, Ohishi M.
   Different characteristics of mitochondrial dynamics-related miRNAs on the hemodynamics of pulmonary artery hypertension and chronic thromboembolic pulmonary hypertension.
   J Cardiol 2021; 78: 24-30.
10. Shimono H, Kajiya T, Takaoka J, Miyamura A, Inoue T, Kitazono K, Ninomiya T, Atsuchi Y, Atsuchi N, Ohishi M.
    Characteristics of recurrent in-stent restenosis (ISR) after second and third generation drug-eluting stent (DES) implantation.
    Cor Art Dis 2021; 32: 36-41.
11. Yoshimoto I, Iriki Y, Oketani N, Okui H, Ichiki H, Maenosono R, Namino F, Miyata M, Ohishi M.
    A randomized comparison of two direct oral anticoagulants for patients undergoing cardiac ablation with a contemporary warfarin control arm.
    J Interv Card Electrophysiol 2021; 60: 375-385.
12. Uchikado Y, Ikeda Y, Sasaki Y, Iwabayashi M, Akasaki Y, Ohishi M.
    Association of lectin-like oxidized low-density lipoprotein receptor-1 with angiotensin II type 1 receptor impacts mitochondrial quality control, offering promise for the treatment of vascular senescence.
    Front Cardiovasc Med 2021; 8: 788655.
13. Nakamura M, Hamada T, Tanaka A, Nishi K, Kume K, Goto Y, Beppu M, Hijioka H, Higashi Y, Tabata H, Mori K, Mishima Y, Uchino Y, Yamashiro K, Matsumura Y, Makizako H, Kubozono T, Tabira T, Takenaka T, Ohishi M, Sugiura T.
    Association of oral hypofunction with frailty, sarcopenia, and mild cognitive impairment: A cross-sectional study of community-dwelling Japanese older adults.
    J Clin Med 2021; 10: 1626. J Clin Med 2021; 10 (8): 1626.
14. Nakajo M, Ojima S, Kawakami H, Tani A, Hirayama A, Jinguji M, Kubozono T, Ohishi M, Yoshiura T.
    Value of patlak ki images from 18F-FDG-PET/CT for evaluation of the relationships between disease activity and clinical events in cardiac sarcoidosis.
    Sci Rep 2021; 11: 2729.
15. Kiuchi Y, Makizako H, Nakai Y, Tomioka K, Taniguchi Y, Kimura M, Kanouchi H, Takenaka T, Kubozono T, Ohishi M.
    The association between dietary variety and physical frailty in community-dwelling older adults.
    Healthcare 2021; 9: 32.
16. Kaimoto K, Yamashita M, Suzuki T, Makizako H, Koriyama C, Kubozono T, Takenaka T, Ohishi M, Kanouchi H, Tarumizu Study Diet Group.
    Association of protein and magnesium intake with prevalence of prefrailty and frailty in community-dwelling older Japanese women.
    J Nutr Sci Vitaminol 2021; 67: 39-47.
17. Maruta M, Makizako H, Ikeda Y, Miyata H, Nakamura A, Han G, Shimokihara S, Tokuda K, Kubozono T, Ohishi M, Tabira T.
    Association between apathy and satisfaction with meaningful activities in older adults with mild cognitive impairment: A population-based cross-sectional study.
    Int J Geriatr Psychiatry 2021; 36: 1065-1074.
18. Maenosono R, Mizukami N, Ichiki H, Oketani N, Namino F, Masamoto I, Yuasa T, Yamakuchi M, Ohishi M, Hashiguchi T.
    Total atrial conduction time as a possible predictor of atrial fibrillation recurrence after catheter ablation for paroxysmal atrial fibrillation: relationship between electrical atrial remodeling and structural atrial remodeling time courses.
    J Med Ultrason 2021; 48: 295-306.
19. Sugimoto T, Araki A, Fujita H, Honda K, Inagaki N, Ishida T, Kato J, Kishi M, Kobayashi K, Kouyama K, Noma H,Ohishi M, Satoh-Asahara N, Shimada H, Sugimoto K, Suzuki S, Takeya Y, Tamura Y, Tokuda H, Umegaki H, Watada H, Yamada Y, Sakurai T.
    The multi-domain intervention trial in older adults with diabetes mellitus for prevention of dementia in Japan: study protocol for a multi-center, randomized, 18-month controlled trial.
    Front Aging Neurosci 2021; 13: 680341.
20. Inoue K, Hirao K, Kumagai K, Kimura M, Miyauchi Y, Tsushima E, Ohishi M, Kimura K, Yasaka M, Yamaji H, Okawa K, Fujimoto M.
    Long-term efficacy and safety of anticoagulation after atrial fibrillation ablation: data from the JACRE registry.
    J Cardiol 2021; 77: 263-270.
21. Salim Anwar A, Kawasoe S, Kubozono T, Ojima S, Kawabata T, Ikeda Y, Miyahara H, Tokushige K, Ohishi M.
    Assessment of future hypertension risk by sex using combined body mass index and waist-to-height ratio.
    Circ Rep 2021 Nov 20;4: 9-16.

Shin KAWASOE

1. Kubozono T, Akasaki Y, Kawasoe S, Ojima S, Kawabata T, Makizako H, Kuwahata S, Takenaka T, Maeda M, Ohno M, Kijimuta M, Fujiwara S, Miyagawa K, Ohishi M.
   The relationship between home blood pressure measurement and room temperature in a Japanese general population.
   Hypertens Res 2021; 44: 454-463.
2. Ninomiya Y, Kawasoe S, Kubozono T, Tokushige A, Ichiki H, Miyahara H, Tokushige K, Ohishi M.
   Sex-specific relationship between abdominal obesity and new-onset atrial fibrillation in the general Japanese population.
   Heart Vessels 2021; 36: 1879-1884.
3. Kawasoe S, Kubozono T, Ojima S, Kawabata T, Miyahara H, Tokushige K, Ohishi M.
   J-shaped curve for the association between serum uric acid levels and the prevalence of blood pressure abnormalities.
   Hypertens Res 2021; 44: 1186-1193.
4. Ojima S, Kubozono T, Kawasoe S, Kawabata T, Miyahara H, Tokushige K, Ohishi M.
   Gender differences in the risk factors associated with atherosclerosis by carotid intima-media thickness, plaque score, and pulse wave velocity.
   Heart Vessels 2021; 36: 934-944.
5. Seki T, Takeuchi M, Kawasoe S, Takeuchi K, Miki R, Ueshima K, Kawakami K.
   Survival benefits of outpatient cardiac rehabilitation after acute myocardial infarction: propensity analysis using japanese administrative database.
   Ann Clin Epidemiol 2021: 3; 10-26.
6. Salim Anwar A, Kawasoe S, Kubozono T, Ojima S, Kawabata T, Ikeda Y, Miyahara H, Tokushige K, Ohishi M.
   Assessment of future hypertension risk by sex using combined body mass index and waist-to-height ratio.
   Circ Rep 2021; 4: 9-16.
7. Kawasoe S, Kubozono T, Ojima S, Kawabata T, Miyahara H, Tokushige K, Ohishi M.
   Sex differences in the effects of weight reduction on future blood pressure elevation in a mildly obese middle-aged population.
   Circ Rep 2020; 2: 385-392.
8. Ojima S, Kubozono T, Kawasoe S, Kawabata T, Miyata M, Miyahara H, Maenohara S, Ohishi M.
   Association of risk factors for atherosclerosis, including high-sensitivity C-reactive protein, with carotid intima-media thickness, plaque score, and pulse wave velocity in a male population.
   Hypertens Res 2020;43: 422-430.
9. Ojima S, Kubozono T, Kawasoe S, Kawabata T, Miyata M, Miyahara H, Maenohara S, Ohishi M.
   Association of risk factors for atherosclerosis, including high-sensitive C-reactive protein, with carotid intima-media thickness, plaque score and pulse wave velocity in male population.
   Hypertens Res 2020 May;43(5):422-430.
10. Kawasoe S, Ide K, Usui T, Kubozono T, Yoshifuku S, Miyahara H, Maenohara S, Ohishi M, Kawakami K.
    Distribution and characteristics of hypouricemia within the japanese general population: a cross-sectional study.
    Medicina (Kaunas) 2019; 55: E61.

Akihiro TOKUSHIGE

1. Ninomiya Y, Kawasoe S, Kubozono T, Tokushige A, Ichiki H, Miyahara H, Tokushige K, Ohishi M.
   Sex-specific relationship between abdominal obesity and new-onset atrial fibrillation in the general Japanese population.
   Heart Vessels 2021; 36: 1879-1884.
2. Arikawa R, Kanda D, Ikeda Y, Tokushige A, Sonoda T, Anzaki K, Ohishi M.
   Prognostic impact of malnutrition on cardiovascular events in coronary artery disease patients with myocardial damage.
   BMC Cardiovasc Disord 2021; 21: 479.
3. Iwatani N, Kubota K, Ikeda Y, Tokushige A, Miyanaga S, Higo K, Ohishi M.
   Different characteristics of mitochondrial dynamics-related miRNAs on the hemodynamics of pulmonary artery hypertension and chronic thromboembolic pulmonary hypertension.
   J Cardiol 2021; 78: 24-30.
4. Kawabe A, Yasu T, Morimoto T, Tokushige A, Momomura SI, Sakakura K, Node K, Inoue T, Ueda S; CHD Collaborative Investigators.
   WBC count predicts heart failure in diabetes and coronary artery disease patients: a retrospective cohort study.
   ESC Heart Fail 2021; 8: 3748-3759.
5. Kubota K, Miyanaga S, Iwatani N, Higo K, Tokushige A, Ikeda Y, Ohishi M.
   Geriatric Nutritional Risk Index is associated with prognosis in patients with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.
   Circ Rep 2020; 2: 372-377.
6. Kanda D, Ikeda Y, Sonoda T, Tokushige A, Kosedo I, Yoshino S, Takumi T, Ohishi M.
   Malnutrition and non-use clopidogrel additively aggravate prognosis of critical limb ischemia patients who underwent revascularization.
   Circ Rep 2020; 2: 121-127.
7. Kosedo I, Tokushige A, Takumi T, Yoshikawa A, Teraguchi K, Takenouchi K, Shiraishi K, Ikeda D, Imamura M, Sonoda T, Kanda D, Ikeda Y, Ido A, Ohishi M.
   Use of proton pump inhibitors is associated with an increase in adverse cardiovascular events in patients with hemodialysis: insight from the KIDS Registry.
   Eur J Intern Med. 2020 Feb;72:79-87.
8. Kinjo T, Tadokoro T, Tokushige A, Zamami T, Taira S, Ikehara Y, Tsuhako C, Ohtsu H, Ueda S, Kakinohana M.
   Effects of perioperative administration of acetaminophen on postoperative shivering: a randomized, triple-blind, placebo-controlled trial.
   Anesth Analg 2020; 130: 983-990.
9. Nagata M, Ito H, Yoshida T, Tokushige A, Ueda S, Yokose T, Nakayama H.J
   Risk factors for progressive sarcopenia 6 months after complete resection of lung cancer: what can thoracic surgeons do against sarcopenia?
   Thorac Dis 2020; 12: 307-318.
10. Shinoura S, Tokushige A, Chinen K, Mori H, Kato S, Ueda S.
    Association between contrast-induced nephrotoxicity and contrast enhanced computed tomography followed by endoscopic retrograde cholangiopancreatography.
    Eur J Radiol 2020; 129: 109074.

Research Grant List

Mitsuru OHISHI

Shin KAWASOE

Akihiro TOKUSHIGE