• Research outline
• Research interests
• Staff
• Research results
• Research Grant List

Research outline

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Research interests

• Postoperative pain, inflammation and wound healing
• Investigation of a marker for perioperative acute renal injury
• Perioperative transfusion and influence of anesthetics in diabetic patients
• The effects of anesthetics on hepatic ischemia and reperfusion injury
• Analgesic effects of odor

Staff

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Research results

Yuichi KANMURA

• Hasegawa-Moriyama M, Nakahara M, Saito T, Yamada T, Mukaihara K, Masuda M, Matsunaga A, Kanmura Y. The effects of glucose load on catabolism during remifentanil-based anesthesia in patients with diabetes mellitus: a prospective randomized trial. Open Journal of Anesthesiology, Vol.5, No.7, pp.155-162 (2015).
• Moriyama T, Matsunaga A, Nagata O, Enohata K, Kamikawaji T, Uchino E, Kanmura Y. Effective method of continuous rocuronium administration based on effect-site concentrations using a pharmacokinetic/pharmacodynamic model during propofol-remifentanil anesthesia. J Anesth. 2015 ahead of print
• Kuroki C, Godai K, Hasegawa-Moriyama M, Kuniyoshi T, Matsunaga A, Kanmura Y, Kuwaki T. Perfusion index as a possible predictor for postanesthetic shivering. J Anesth 28(1):19-25(2014).
• Godai K, Hasegawa-Moriyama M, Kurimoto T, Saito T, Yamada T, Sato T, Kojima M, Kanmura Y. Peripheral administration of morphine attenuates postincisional pain by regulating macrophage polarization through COX-2-dependent pathway. Molecular Pain Vol.10, No.1, pp.36 (2014).
• Kuroki C, Takahashi Y, Ootsuka Y, Kanmura Y, Kuwaki T. The Impact of Hypothermia on Emergence from Isoflurane Anesthesia in Orexin Neuron-Ablated Mice. Anesth Analg 116(5):1001-5 (2013).
• Hasegawa-Moriyama M, Kurimoto T, Nakama M, Godai K, Kojima M, Kuwaki T, Kanmura Y Peroxisome proliferator-activated receptor-gamma agonist rosiglitazone attenuates inflammatory pain through the induction of heme oxygenase-1 in macrophages PAIN 154:1402-1412 (2013).
• Nakahara M, Ito T, Kawahara K, Yamamoto M, Nagasato T, Shrestha B, Yamada S, Miyauchi T, Higuchi K, Takenaka T, Yasuda T, Matsunaga A, Kakihana Y, Hashiguchi T, Kanmura Y, Maruyama I. Recombinant thrombomodulin protects mice against histone-induced lethal thromboembolism. PLoS One. 8(9): e75961 (2013).
• Kakihana Y, Okayama N, Matsunaga A, Yasuda T, Imabayashi T, Nakahara M, Kiyonaga N, Ikoma K, Kikuchi T, Kanmura Y, Oda M, Ohmae E, Suzuki T, Yamashita Y, Tamura M. Cerebral monitoring using near-infrared time-resolved spectroscopy and postoperative cognitive dysfunction. Adv Exp Med Biol. 737:19-24, 2012.
• Takeyama M, Matsunaga A, Kakihana Y, Masuda M, Kuniyoshi T, Kanmura Y. Impact of skin incision on the pleth variability index. J Clin Monit Comput. 25:215-21, 2011.
• Imakiire N, Omae T, Matsunaga A, Sakata R, Kanmura Y. Can a NICO monitor substitute for thermodilution to measure cardiac output in patients with coexisting tricuspid regurgitation? J Anesth. 24:511-7, 2010.
• Kakihana Y, Matsunaga A, Yasuda T, Imabayashi T, Kanmura Y, Tamura M.　Brain oxymetry in the operating room: current status and future directions with particular regard to cytochrome oxidase. J Biomed Opt. 13:033001, 2008.
• Ohmae E, Oda M, Suzuki T, Yamashita Y, Kakihana Y, Matsunaga A, Kanmura Y, Tamura M.　 Clinical evaluation of time-resolved spectroscopy by measuring cerebral hemodynamics during cardiopulmonary bypass surgery. J Biomed Opt. 12:062112, 2007.
• Matsunaga A, Shah PM, Raney AA. Impact of intraoperative echocardiography/surgery team on successful mitral valve repair: a community hospital experience. J Heart Valve Dis. 14:325-331, 2005.
• Kakihana Y, Matsunaga A, Tobo K, Isowaki S, Kawakami K, Tsuneyoshi I, Kanmura Y, Tamura M. Redox behavior of cytochrome oxidase and neurological prognosis in 66 patients who underwent thoracic aortic surgery. Eur. J. Cardiothorac. Surg. 21:434-439, 2002.
• Matsunaga A, Nomura Y, Tamura M, Kuroda S, Nishihira J, Yoshimura N. Energy-dependent redox state of heme a+a3 and copper of cytochrome oxidase in perfused rat brain in situ. Am. J. Physiol. 275(Cell Physiol. 44):C1022-C1030, 1998.

Research Grant List

Yuichi KANMURA

Maiko HASEGAWA

Takahiro MORIYAMA

Tetsuya OHNO

黒木千晴

Mayumi NAKAHARA

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