FIELD

Research outline

心身内科学スタッフ

Graduate School Graduate School of Medical and Dental Sciences
Course Health Research Cource
Field Social and Behavioral Medicine
Department Psychosomatic Internal Medicine
Homepage http://www.kufm.kagoshima-u.ac.jp/~psm/

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Contact

TEL.+81-99-275-5751 / FAX.+81-99-275-5749

Research interests

  • Mind-body correlation
  • The mechanisms of appetite and feeding
  • Advanced researches Kampo formula

Staff

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Professor
Name Akio INUI
Specialized field Psychosomatic Internal Medicine
Research interests ・食欲体重調節
・心身症
・漢方
・統合医療

Researche Repository


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Associate Professor
Name Akihiro ASAKAWA
Specialized field Psychosomatic Internal Medicine
Research interests ・難治、根治、予防、健康増進
・アンチエージング
・終末期医療

Researche Repository


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Assistant Professor
Name Akinori MORINAGA
Specialized field 漢方医学
Research interests ・漢方
・食欲体重調節

Researche Repository


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Lecturer
Name Goro KATSUURA
Specialized field 内分泌代謝学
Research interests ・補完医療に関する基礎研究
・食欲及び摂食のメカニズムに関する基礎研究

Researche Repository


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Lecturer
Name Koji ATAKA
Specialized field ストレス科学
Research interests ・心身相関
・脳骨髄相関

Researche Repository


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Lecturer
Name Kai-Chun Cheng
Specialized field 内分泌代謝学
Research interests ・補完医療に関する基礎研究
・肥満,糖尿病及び悪液質の病態解析

Researche Repository

Research results

Akio INUI
  1. Amitani M, Cheng K, Asakawa A, Amitani H, Kairupan TS, Sameshima N, Shimizu T, Hashiguchi T, Inui A. Allantoin ameliorates chemically-induced pancreatic β-cell damage through activation of the imidazoline I3 receptors. PeerJ. 2015; 3: e1105.
  2. Haruta I, Fuku Y, Kinoshita K, Yoneda K, Morinaga A, Amitani M, Amitani H, Asakawa A, Sugawara H, Takeda Y, Bowers CY, Inui A. One-year intranasal application of growth hormone releasing peptide-2 improves body weight and hypoglycemia in a severely emaciated anorexia nervosa patient. J Cachexia Sarcopenia Muscle. 2015 Sep;6(3):237-41.
  3. Li Y, Cheng KC, Asakawa A, Amitani H, Takimoto Y, Runtuwene J, Inui A. Activation of imidazoline-I3 receptors ameliorates pancreatic damage. Clin Exp Pharmacol Physiol. 2015.
  4. Runtuwene J, Amitani H, Amitani M, Asakawa A, Cheng KC, Inui A. Hydrogen-water enhances 5-fluorouracil-induced inhibition of colon cancer. PeerJ. 2015; 3: e859.
  5. Yoshizaki Y, Kawasaki C, Cheng KC, Ushikai M, Amitani H, Asakawa A, Okutsu K, Sameshima Y, Takamine K, Inui A. Rice koji reduced body weight gain, fat accumulation, and blood glucose level in high-fat diet-induced obese mice. Peer J. 2014; 2: e540.
  6. Cheng KC, Asakawa A, Li YX, Chung HH, Amitani H, Ueki T, Cheng JT, Inui A. Silymarin Induces Insulin Resistance through an Increase of Phosphatase and Tensin Homolog in Wistar Rats. PLoS One. 2014; 9: e84550
  7. Takagi K, Legrand R, Asakawa A, Amitani H, Fran?ois M, Tennoune N, Co?ffier M, Claeyssens S, do Rego JC, D?chelotte P, Inui A, Fetissov SO. Anti-ghrelin immunoglobulins modulate ghrelin stability and its orexigenic effect in obese mice and humans. Nat Commun. 2013; 4: 2685.
  8. Li YX, Cheng KC, Asakawa A, Kato I, Sato Y, Amitani H, Kawamura N, Cheng JT, Inui A. Role of musclin in the pathogenesis of hypertension in rat. PLoS One. 2013; 8: e72004.
  9. Amitani M, Asakawa A, Amitani H, Kaimoto K, Sameshima N, Koyama KI, Haruta I, Tsai M, Nakahara T, Ushikai M, Cheng KC, Hamada S, Inui A. Plasma klotho levels decrease in both anorexia nervosa and obesity. Nutrition. 2013; 29: 1106-9.
  10. Amitani H, Asakawa A, Ogiso K, Nakahara T, Ushikai M, Haruta I, Koyama K, Amitani M, Cheng K, Inui A. The role of adiponectin multimers in anorexia nervosa. Nutrition. 2013; 29: 203-206.
  11. Amitani H, Asakawa A, Cheng KC, Amitani M, Kaimoto K, Nakano M, Ushikai M, Li Y, Tsai M, Li JB, Terashi M, Chaolu H, Kamimura R, Inui A. Hydrogen improves glycemic control in type 1 diabetic animal model by promoting glucose uptake into skeletal muscle. PLoS One. 2013; 8: e53913.
  12. Ogiso K, Asakawa A, Amitani H, Nakahara T, Ushikai M, Haruta I, Koyama KI, Amitani M, Harada T, Yasuhara D, Inui A. Plasma nesfatin-1 concentrations in restricting-type anorexia nervosa. Peptides. 2011; 32: 150-3.
  13. Tanaka C, Asakawa A, Ushikai M, Sakoguchi T, Amitani H, Terashi M, Cheng K, Chaolu H, Nakamura N, Inui A. Comparison of the anorexigenic activity of CRF family peptides. Biochem Biophys Res Commun. 2009; 390: 887-91.
  14. Kojima S, Asakawa A, Amitani H, Sakoguchi T, Ueno N, Inui A, Kalra SP. Central leptin gene therapy, a substitute for insulin therapy to ameliorate hyperglycemia and hyperphagia, and promote survival in insulin-deficient diabetic mice. Peptides. 2009 May;30(5):962-6.
  15. Fujitsuka N, Asakawa A, Hayashi M, Sameshima M, Amitani H, Kojima S, Fujimiya M, Inui A. Selective Serotonin Reuptake Inhibitors Modify Physiological Gastrointestinal Motor Activities via 5-HT2c Receptor and Acyl Ghrelin. Biological Psychiatry. 2009; 65: 748-59.

Patents and copy Rights

titleinventor
/application number
application date
悪液質改善剤 Akio INUI、Akihiro ASAKAWA
特願2010‐274339
平成22年12月9日
赤米抽出物を含む酒酔い又は二日酔い防止・回復用組織物 鄭凱駿
特願2014‐173178
平成26年8月27日

Collaborations

・株式会社 新日本科学「霊長類を用いた疾患モデルの作出」

For production study

Akio INUI
  • 重点領域研究「食と健康」研究推進プロジェクト

Research Grant List

Akio INUI
Project・Event / Span 科学研究助成事業 挑戦的萌芽研究 平成27年度~平成27年度
Research 食欲調節ペプチド自己抗体のクローニングとその意義の解明
-グレリンを中心に-
Project・Event / Span 科学研究費助成事業 基盤研究(C)分担
Research 加齢性疾患を目的としたバイオマーカーの検討
Akihiro ASAKAWA
Project・Event / Span 二国間交流事業
Research サルコペニアの病態解明と治療法の開発
‐新規筋由来ペプチドからのアプローチ‐
Project・Event / Span 科学研究費助成事業 基盤研究(C)分担
Research 加齢性疾患を目的としたバイオマーカーの検討
Koji Ataka
Project・Event / Span 科学研究費助成事業 基盤研究(C)
Research 心身相関に関与する新たな因子「骨髄由来細胞」の同定と摂食障害での脳骨髄相関の解明

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